Prognosis of autoimmune pulmonary alveolar proteinosis

• One hundred and three patients diagnosed at Tohoku University, Niigata University, and Kyorin University Hospitals, from 1999 to 2017, were retrospectively investigated from the present to the past.
• The survival rates (average [95% confidence interval]) of diagnosed patients 2, 5, and 11 years later were found to be 99.1 [97.1–100], 97.7 [94.5– 1.00], and 86.2 [76.5–97.1] %, respectively.
• If we divide these subjects into those whose predicted lung diffusing capacity (%Dlco) at the time of diagnosis was 75.7% or more from those whose %Dlco was less than 75.7%, we find that the former were all alive after 10 years, whereas 34.8 [0–64.1]% of the latter patients died within 10 years.